CBD oil and diabetes

October 22, 2021

In recent years, CBD oil has gained popularity as a safe and efficient therapy for various common illnesses, and diabetes is no exception. Among Americans, diabetes is becoming an increasingly common illness. It affects an estimated 30 million individuals, all of whom must live with the unpleasant symptoms of this incurable disease daily.

Fortunately, CBD oil is showing promise as a treatment option for various diabetes-related problems and symptoms, including nausea and vomiting.

The Advantages of Using CBD Oil for Type 2 Diabetes

A total of 1.5 million Americans are diagnosed with diabetes every year, with the majority of them being type 1 or type 2. A large number of others are deemed to be “prediabetic.” Prediabetic individuals do not exhibit the same symptoms as diabetic individuals. Still, they are at a much-increased risk of developing full-blown diabetes if they do not make significant adjustments in their lifestyle.

Even though making adjustments to one’s diet and increasing one’s physical activity may be very helpful in preventing and managing type 2 diabetes, implementing these changes might be difficult at first. Many individuals do not have the time or energy to cook nutritious meals regularly, and exercise may be difficult for overweight or have mobility problems. As a result, many physicians prescribe medicines to help patients manage the symptoms of type 2 diabetes; nevertheless, these treatments are not without their own set of adverse effects.

Considering that CBD oil has been shown to boost motivation while also alleviating aches and pains, it may be more difficult in the future to make the lifestyle adjustments required to fight diabetes. You may use the information in this table as a starting point of reference if you are already taking medication for type 1 or type 2 diabetes and are interested in incorporating CBD oil into your health routine. However, before taking any action, you must consult with your doctor about the dangers of mixing CBD with your diabetic prescription.

CBD Oil Has several Potential Advantages


It is used to decrease blood sugar levels in people with both Type 1 and Type 2 diabetes.

Although there are no known interactions between CBD oil and Metformin, this does not rule out the possibility of such interactions occurring; don’t hesitate to get in touch with your doctor before using CBD oil and Metformin together. CBD oil has been proven to help with nausea and pain reduction.


It aids in the breakdown of glucose in the body. The insulin produced by the body of type 1 diabetics is insufficient, and the insulin produced by certain type 2 diabetics is not used correctly. This necessitates the need for them to take it externally.

Hypoglycemia, rash, headache, weight gain, anxiety, and sadness are among the symptoms of diabetes. Although there are no documented interactions between CBD oil and insulin, this does not rule out the possibility of such interactions occurring. Before using any medication, always contact your doctor.

CBD oil has been proven to be effective in the treatment of pain and the management of anxiety and depression.

Sulfonylureas are a kind of antibiotic (DiaBeta; Glynase; Glucotrol; Amaryl)

It is used to assist people with type 2 diabetes in producing more insulin. Hunger, weight gain, indications of low blood sugar, sweating, dizziness, disorientation, upset stomach, and dark-colored urine are all possible symptoms.

There are no documented interactions between CBD oil and Sulfonylureas, but it does not rule out the possibility of such interactions occurring. Always contact your doctor before using CBD oil.

Meglitinides are a kind of antibiotic (Prandin; Starlix)

Working similarly to sulfonylureas, it assists the pancreas in secreting more insulin in people with type 2 diabetes. Low blood sugar, weight gain, and joint discomfort are all symptoms of diabetes.

Although there are no documented interactions between CBD oil and Meglitinides, this does not rule out the possibility of such interactions occurring. Before using any medication, always contact your doctor.

DPP-4 inhibitors are drugs that block the enzyme DPP-4 (Januvia; Onglyza; Tradjenta)

Contribute to the reduction of blood sugar levels

Pain in the joints; higher chance of developing pancreatitis

There are no documented interactions between CBD oil and DPP-4 inhibitors, but this does not rule out the possibility of such interactions occurring. Always contact your doctor before using CBD oil.

Agonists of the GLP-1 receptor (Bydureon; Byetta; Victoza; Ozempic)

Slows digestion, allowing for weight loss and a reduction in blood sugar levels.

Increased risk of pancreatitis; nausea, and vomiting

There are no documented interactions between CBD oil and GLP-1 receptor agonists, but this does not rule out the possibility of such interactions occurring. Always check with your doctor before using CBD oil.

Inhibitors of SGLT2 (Invokana; Farxiga; Jardiance)

It prevents the kidneys from reabsorbing glucose into the bloodstream, allowing it to be discharged in the urine.

Vaginal yeast infections, urinary tract infections, low blood pressure, a greater risk of diabetic ketoacidosis, and lower limb amputation are all associated with this condition.

There are no known interactions between CBD oil and SGLT2 inhibitors. However, CBD has been proven to decrease blood pressure; always check with your doctor before using CBD oil or other supplements. It is probably better not to mix CBD oil with SGLT2 inhibitors to prevent a potentially hazardous decrease in blood pressure.

The Efficacy of CBD Oil in the Treatment of Diabetes

Insulin resistance and diabetic neuropathy are two of the problems that CBD oil may assist diabetic patients with.

CBD Oil for the Treatment of Insulin Resistance

Insulin resistance is one of the most frequent issues that people with prediabetes and type 2 diabetes have to deal with daily. It happens when the body rejects insulin, a necessary chemical to maintain stable blood sugar levels. Insulin resistance leads to a rise in blood glucose levels, which causes damage to neurons, blood vessels, and other critical organs.

Even though the precise mechanism by which CBD oil combats insulin resistance remains a mystery, studies have revealed a link between insulin resistance and inflammation. The fact that CBD is known to control inflammation via its effects on both the endocannabinoid system and the immune system suggests that it may enhance the health of people with diabetes.

CBD oil also has the additional effect of increasing the amount of the neurotransmitter adenosine in the brain. These changes affect the A1 and A2 adenosine receptors, which are important in reducing inflammation in cells. As a result of raising the amount of adenosine accessible, CBD is believed to enhance signaling by the A1 and A2 receptors, which experts think is associated with its anti-inflammatory properties.

The various methods through which CBD reduces inflammation may be the key to treating insulin resistance. Only time and more study will be able to answer this question.

CBD Oil for the Treatment of Diabetic Neuropathy

CBD oil is thought to effectively reduce the neuropathic (nerve) pain experienced by people with diabetes by acting on cannabinoid receptors in the endocannabinoid system, both directly and via indirect actions on these receptors. CBD affects the CB2 cannabinoid receptors, which are located throughout the central nervous system and are responsible for pain relief. CB2 receptors are believed to be involved in the regulation of pain and inflammation, and investigations have shown that almost all human illnesses are associated with some level of malfunction at the CB2 receptor level.

Approximately 64 individuals with multiple sclerosis participated in a trial conducted by the University of Liverpool. Multiple sclerosis is a disease that, like diabetes, causes severe neuropathic pain. In this study, the participants were divided into two groups, with one getting a placebo and the other receiving a THC: CBD oromucosal spray. Compared to the control group, the test group showed significant reductions in pain and slept disruption after just four weeks.

According to research, cannabinoids such as cannabidiol (CBD) can improve the function of inhibitory receptors in the central nervous system. For example, in the case of glycine receptors, they play a critical part in the perception of pain by the body. According to the findings, researchers who studied these receptors discovered that glycinergic cannabinoids like CBD are “excellent therapeutic agents in the treatment of inflammatory and neuropathic pain,” according to the findings.

Second research, conducted by the University of California, investigated the potential benefits of using vaporized cannabis to treat neuropathic pain. According to the study’s findings, cannabis has analgesic effects that are comparable to those of two of the most frequently prescribed prescription pain medicines.

Given the encouraging findings observed in several different studies on the use of CBD for neuropathic pain and the potential benefits outweighing the reported adverse effects, CBD oil may be a strong tool for you to explore if you are suffering nerve pain as a consequence of diabetes.

How to Use Cannabidiol for Diabetes Treatment

It is advisable to consult with your doctor before considering using CBD oil to treat the symptoms of diabetes that you are experiencing. While CBD is generally considered harmless, it may interact with some prescription drugs, such as certain antibiotics and antidepressants. By consulting with your doctor, you may prevent unpleasant drug interactions and devise a safe treatment strategy for your condition or illness.

CBD oil is available in several different delivery forms. The CBD oil capsules and inhalants, such as CBD vape oils and CBD flower, are the most convenient options for many individuals since they are the most familiar and comfortable forms.

CBD oil capsules may be included in a daily supplement regimen and will operate in the background to assist in the restoration of balance in the body. This is because your digestive system must break down the capsules before the CBD can be processed via your liver and absorbed into your circulation, making them unsuitable for pain relief when you need it right away. On the other hand, the effects will usually last 4-6 hours, making capsules an excellent choice for managing chronic pain or inflammation throughout the day.

CBD vapes and CBD flowers are the most effective forms of pain treatment. The CBD is absorbed immediately by the lungs, allowing for the delivery of maximum effects in as little as a couple of minutes. Unfortunately, the benefits of CBD vapes and flowers are usually short-lived, lasting anywhere from 30 minutes to an hour on average.

CBD oil tinctures or drops are helpful when looking for alternatives that will offer long-term advantages while also providing reasonably immediate relief. Drops or tinctures are simple to include in one’s daily routine and are inconspicuous enough to be used for on-the-spot treatment as needed. The effects of CBD tinctures and drops may be felt within a half-hour since the CBD skips the digestive system and is absorbed directly under the tongue. The effects typically last between 2 and 4 hours on average.

Finally, you may want to think about utilizing a CBD oil topical (e.g., a tincture) to treat your condition.

Finally, you may want to think about utilizing a CBD oil topical to treat your condition (e.g., CBD lotion, salve, or gel). The absorption of CBD topicals into the skin may be sluggish, taking an hour or more, but they offer long-lasting focused pain relief. You will often only need to use a CBD topical once per day, if at all. If you suffer from diabetic neuropathy regularly, this tailored treatment may be a godsend.

The bottom line is that a mix of the CBD products listed above may be the most effective strategy for treating the symptoms of diabetic neuropathy. In addition to taking a CBD capsule with your morning coffee and applying a CBD lotion to particular problem areas, you could also carry your CBD vaporizer and/or CBD oil drops with you while at work or out and about for fast relief from acute nerve pain while you’re on the move.

Before considering any of these alternatives, you should get familiar with the legislation in your state. Some CBD oil products may include THC, and although the majority of CBD oil products will have 0.3 percent or less THC (the legal limit), you may come across a full-spectrum product that has much more than that. In addition, there are certain areas where people are not permitted to buy goods containing any level of THC, which means that you may only legally purchase CBD isolate or broad-spectrum products.

Dosage of Cannabidiol for Diabetes

Given that no two individuals are alike, it is difficult to establish a uniform CBD oil dose for diabetes. It is advisable to start by following the dose recommendations found on the information sheet that came with your CBD oil product if one is available.

We at CBD Oil Review have studied hundreds of products and have come up with the following recommendations:

The CBD Oil Review Serving Standard is 25mg of CBD taken twice daily, as recommended by the company.

For those who do not get relief from this dose, we suggest increasing the serving size by 25mg every 3-4 weeks until you do.

Check out our guide for additional information on doses, as well as some helpful hints for getting it right the first time. Alternatively, a naturopathic doctor who is experienced in using CBD oil to treat a wide range of medical problems may provide you with more customized dose recommendations.

The Most Effective CBD Oils for Diabetics

The finest CBD oil for diabetes will be tailored to your specific requirements and manufactured by a reputable company. Because the CBD oil business is still unregulated, you must be careful in your research to verify that you are only purchasing from firms that have good intentions and provide high-quality goods. Here’s what you should look for:

Transparency. The CBD extracts of a reputed brand will be tested, and the Certificates of Analysis will be made available for you to see online. Certificates of Analysis will enable you to confirm the stated CBD and THC concentrations while also verifying that your product does not contain any unexpected and potentially dangerous additions or compounds.

Organic is the way to go. Look for companies that get their CBD oil products from certified organic hemp, ensuring that the final product is free of pesticides and herbicides. CBD oil is derived from hemp that has been certified organic.

Ingredients should be read. Please pay attention to the contents list when purchasing CBD oil products; they shouldn’t include much more than CBD and a carrier liquid such as hemp seed oil or MCT coconut oil, among other things. Some products may include additional cannabinoids and terpenes derived from the whole hemp plant, while others will be scented with natural ingredients such as cinnamon or orange oil. These natural additives are completely acceptable and may even offer advantages that are enhanced in certain cases. Avoid goods that include unneeded additives, preservatives, and other artificial components, and instead, choose natural alternatives.

Researchers are still investigating the potential benefits of CBD oil for diseases such as diabetes. In the months and years ahead, we should better understand how CBD may benefit patients. But, in the meanwhile, if you are interested in experimenting with CBD oil to control your diabetic symptoms, do your homework and consult with your doctor first.

Type 1 and type 2 diabetes affect individuals of all ages and from all socioeconomic and ethnic origins. While there is currently no cure for diabetes, the symptoms of the disease may be managed with a mix of medicines and a healthy lifestyle adjustment.

Even though cannabidiol (CBD) oil is not a substitute for popular anti-diabetic medicines or insulin, it may be useful in alleviating some of the symptoms of diabetes. There is still more research being done to determine if CBD oil has advantages for diabetics.

To understand how cannabidiol (CBD) may be used to treat the symptoms of diabetes, it is first necessary to understand the illness itself.

Type 1 Diabetes vs. Type 2 diabetes

A condition known as diabetes develops when the body cannot produce enough insulin, resulting in high blood sugar levels. Type 1 and type 2 diabetes are the most prevalent forms of diabetes. Type 1 diabetes is diagnosed in 10% of individuals with diabetes, and type 2 diabetes is diagnosed in 80-90 percent of people with diabetes.

Gestational diabetes is a kind of diabetes that develops during pregnancy and is the third most common. Although gestational diabetes resolves after the child’s birth, it may be a predictor of type 2 diabetes later in life if it is not treated.

Type 1 (sometimes known as the first type)

Type 1 diabetes, in contrast to type 2 diabetes, is incurable. Type 1 diabetes develops when a person’s immune system assaults the cells in their pancreas that produce insulin. Type 1 diabetes, formerly known as “juvenile diabetes,” may occur in children and adults and is linked to obesity.

If you have type 1 diabetes, you may encounter any of the following signs and symptoms:

  • The sensation of having excessive thirst and urination
  • Excessive desire to eat
  • Fatigue
  • Loss of weight
  • The hazy vision

The following are some of the most severe symptoms of diabetic ketoacidosis:

  • Skin that is parched
  • Breath that smells like fruit
  • nausea or stomach discomfort
  • a feeling of being out of breath
  • Confusion and a lack of concentration

Type 2 (also known as Type 2 diabetes)

Type 2 diabetes is most likely what comes to mind when you think about diabetes. Adult-onset type 2 diabetes is more common than juvenile-onset diabetes because it is linked with obesity and unhealthy lifestyle choices. Insulin resistance and insulin insufficiency are two characteristics of the disease.

In the case of type 2 diabetes, you may encounter the following signs and symptoms:

  • The sensation of having excessive thirst and urination
  • Excessive desire to eat
  • Fatigue
  • The hazy vision
  • A feeling of numbness or tingling in the hands and feet
  • Sores that don’t seem to heal
  • Loss of weight

Moreover, as the illness develops, type 2 diabetes may result in more severe health complications such as the following:

  • Heart disease is a medical condition that affects the heart.
  • Stroke
  • Kidney disease is a serious condition.
  • The disease of the eyes
  • Diseases of the teeth and gums
  • Damage to the nerves
  • Dementia
  • Depression

What Is the Mechanism of CBD Action?

CBD oil is a cannabinoid present in hemp and cannabis plants, and its chemical composition is very similar to that of tetrahydrocannabinol. CBD oil has been shown to have several health benefits (THC). On the other hand, CBD does not have any mind-altering effects, which is a key factor in its increasing popularity among people of all ages.

THC and CBD both affect the body’s endocannabinoid system (ECS). However, CBD affects cannabinoid receptors that are distinct from THC. So, how does all of this discussion about the ECS relate to the effects of CBD on diabetic complications? The ECS regulates food intake and energy stability, and scientists have shown a link between an overactive ECS and obesity and type 2 diabetes in certain studies. As a consequence of its action at particular receptors, CBD’s effect on the ECS system may be beneficial in managing hyperglycemia, pain, and various byproducts of diabetes, among other things.

The unique characteristics of the chemical make it suitable for a wide variety of therapeutic applications. The advantages of CBD oil are often claimed for a variety of diseases, both connected and unrelated to diabetes, including:

  • Inflammation
  • Pain that lasts for a long period of time
  • Nausea
  • Anxiety and sadness are two emotions that people experience.
  • Seizures
  • Sleep disorders are a kind of sleep problem that occurs when a person does not get enough sleep.

CBD oil is available in various forms, including pills, sublingual drops, topical application (transdermal), and more. Consult with a healthcare practitioner who has prior experience with CBD to determine the appropriate dose for your body.

CBD Adverse Reactions

With the intake of any drug, natural or synthetic, there is the potential of side effects. Due to the possibility of CBD oil interfering with other medications, it is essential to consult your doctor before taking CBD to treat the symptoms of diabetes.

When taking CBD, you may suffer some of the following negative effects:

  • Low blood pressure is a condition in which the blood pressure is too low.
  • Nausea
  • Fatigue
  • Changes in body weight or appetite
  • Diarrhea
  • The feeling of having a dry mouth
  • CBD oil is now being studied as a potential diabetes treatment.

The investigation into CBD and diabetes is not limited to blood sugar levels. From physical symptoms to sadness, CBD oil can be beneficial in the treatment of diabetes in many different ways. However, there have been some intriguing diabetes-specific research discovered.

Diabetes-Related Inflammation and Its Treatment

The results of a 2019 research on diabetic rats revealed that CBD at a dosage of 10 mg per day for 30 days enhanced cognitive function and decreased inflammation. Recent research found that diabetes and aging act together to promote inflammation and memory loss in rats with cerebral hypoperfusion. The current study builds on that finding (i.e., weak blood flow to the brain).

According to earlier research, CBD may be effective in reducing early pancreatic inflammation in type 1 diabetes. Prior research found that cannabidiol lowers the incidence of diabetes in non-obese diabetic mice, which was cited in this article.

Additionally, the cannabidiol may be used to treat diabetic retinopathy, which is a condition that causes blindness in adults. In this case, it’s conceivable that CBD works as an antioxidant by decreasing the absorption of adenosine and thereby lowering retinal inflammation. For this hypothesis to be supported, more clinical trials are needed.

Insulin Resistance and Its Treatment

Double-blind research in animal models discovered that individuals who received 100 mg of CBD twice a day had lower levels of the anti-inflammatory compound resistin. Obesity and insulin resistance are both associated with a high amount of resistin in the blood. According to the findings of the research, CBD may have some effect on insulin resistance.

Current research does not support the notion that CBD may cure diabetes or control blood sugar in a manner that would allow it to be used instead of insulin treatments, statins, and other anti-diabetic medicines. Despite this, ongoing research provides fresh insights into the advantages of CBD oil in terms of enhancing treatment results.

Is CBD Oil a legal substance?

CBD is not currently legal on the federal level. However, it may be legal in your state at the time of writing. Because of the legalization of hemp, however, the future of CBD seems to be bright. Cannabis-derived CBD will become more widely accessible in the future, which is excellent news for people with diabetes who want to benefit from the therapeutic properties of CBD oil.