CBD Oil for Fibromyalgia

October 22, 2021

If you or someone you care about has been diagnosed with fibromyalgia, you know how tough it is to find a treatment for this strange disease. It’s been impossible to establish a conclusive cure for fibromyalgia since the condition is so poorly understood. CBD oil, fortunately, may be able to assist.

While there are few studies on CBD oil and fibromyalgia, the data that is now available suggests it may be useful in lowering fibromyalgia symptoms.

This type of chronic pain is thought to be caused by physically or emotionally distressing events that affect the brain chemistry of the person. The way pain signals are conveyed throughout the central nervous system is affected by these alterations in the brain—two regions that CBD oil is thought to affect.

The Advantages of CBD Oil for Fibromyalgia

The analgesic (pain-relieving) and anti-inflammatory effects of CBD oil are widely known. CBD oil, when combined with its mood-lifting properties, presents a well-rounded fibromyalgia therapeutic option.

Many fibromyalgia sufferers currently use CBD oil, but the most popular treatment strategies include a combination of pain medicines, antidepressants, muscle relaxants, nerve pain drugs, talk therapy, and lifestyle changes.

The traditional therapy procedure has certain drawbacks. Taking pain killers and antidepressants, in particular, is not a good long-term answer, especially because of the negative side effects that can occur with long-term use. When taken in large dosages, over-the-counter pain medications like aspirin and ibuprofen can cause stomach troubles, ulcers, and even cardiovascular problems. Antidepressants can cause sexual problems, emotional numbness, weight gain, and withdrawal symptoms if taken for a long time.

While muscle relaxants may provide some comfort, they should not be used for more than a few weeks because there is little evidence that they are beneficial beyond a short-term treatment program. Nerve pain drugs like Lyrica appear to offer the most hope among standard fibromyalgia therapy options, but they can still cause side effects like drowsiness, edoema, and diarrhea.

Furthermore, several suggested lifestyle adjustments for fibromyalgia sufferers, such as increased exercise, can be difficult to implement due to the disease’s chronic muscle discomfort.

CBD oil is a safer and more natural alternative to the pharmaceuticals that are commonly used to treat fibromyalgia. Cannabidiol (CBD) is being explored extensively for its pain-relieving and mood-enhancing properties without the risk of addiction or negative side effects. CBD oil may be able to replace or supplement the prescriptions you’re taking for fibromyalgia, as well as make prescribed lifestyle modifications more realistic, thanks to its promise of pain-relieving, anti-inflammatory, and mood-boosting properties.

Fibromyalgia: How to Use CBD Oil

The way you utilize CBD oil to treat fibromyalgia will be determined by the symptoms you’re trying to alleviate. However, before you do anything, see your doctor about CBD oil. While cannabidiol is generally believed to be safe with few negative effects, it does have the potential to interact with some drugs, such as antidepressants.

Once your doctor has given you the green light, you’ll need to determine which CBD product(s) you want to utilize. CBD oil vapes, drops, and capsules are some of the most popular and easiest ways to ingest CBD oil, but each one is unique.

CBD vape products give the fastest results of all the CBD oil delivery techniques. The benefits are almost instantaneous because the CBD does not have to pass through the digestive system and is absorbed directly through the lungs. CBD vape oils are ideal for fibromyalgia flare-ups that occur suddenly and unexpectedly. CBD vapes have a short-term effect, lasting anywhere from 30 minutes to an hour. It can be tough to get the dosage correct at first if you’re new to CBD oil or vaping: an inhale for one person may not be the same as an inhale for another. It may take some trial and error to get the right CBD vape dosage for you.

CBD oil capsules, tinctures, and drops are easier to handle in terms of dosage for persons who are new to CBD. Capsules deliver the most constant dose and are simple to include into your existing treatment plan. If you’re not sure how much CBD to take for your fibromyalgia, CBD oil drops and tinctures make it simple to customize your dosage. While these approaches are excellent for controlling CBD dosage, they take longer to work than CBD vapes.

CBD oil capsules must pass through the digestive system and be broken down before they can be absorbed. This means that the effects may take up to an hour to manifest, though you’ll most likely feel the advantages of a capsule (or edible) for at least 4-6 hours. CBD oil drops are absorbed into the bloodstream through the thin skin beneath the tongue, with benefits usually appearing in 30 minutes. CBD oil drops and tinctures have a normal effect time of 2-4 hours, however, this might vary based on your age, weight, and metabolism.

You might use a CBD oil topical, such as a lotion, salve, or gel, to address particular regions of fibromyalgia discomfort. CBD is absorbed through the skin in this format and functions in a highly localized manner. The effects of CBD oil topicals sometimes take a while to kick in, but the advantages linger for hours.

It’ll be up to you to decide which CBD oil is ideal for treating fibromyalgia. It’s possible that a combination of goods will work best for you. Perhaps you take CBD capsules or a CBD tincture every day for long-term treatment, and then utilize a CBD vape oil for pain flare-ups and/or a topical for focused relief. You get to create your own CBD regimen based on your specific requirements.

Dosage of CBD Oil

When it comes to CBD dose for fibromyalgia, getting it right the first time might be challenging. Because everyone absorbs CBD oil differently, there is no single, universal dose. As a result, it’s advisable to start with the smallest serving suggestion on your CBD product and work your way up or down from there. Check out our dosage guide or chat with a naturopathic doctor for assistance and recommendations on how to achieve the proper dose.

However, if you’re looking for a quick beginning point, we at CBD Oil Review have reviewed hundreds of brands and have come up with the following serving recommendation:

25 mg of CBD, taken twice daily, is the CBD Oil Review, Serving Standard.

If you don’t see results after 3-4 weeks, consider increasing your dosage by 25mg every 3-4 weeks until you find a balance.

Treatment of Fibromyalgia with CBD Oil: Is It Effective?

While there isn’t much research on using CBD oil to treat fibromyalgia, the studies that have been done so far on cannabidiol’s effect on fibromyalgia’s most common and bothersome symptoms are promising.

Fibromyalgia Pain Relief with CBD Oil

One of the most common symptoms of fibromyalgia is pain, which CBD oil can help to alleviate. All high-quality CBD oil and medical marijuana come from the cannabis plant. medical CBD extract, CBD isolate, or even full-spectrum CBD oils all are considered CBD legal by the drug administration experts as they are specifically made for medical purposes. Users notice significant pain relief after the first use.

CBD oil has an effect on the body’s endocannabinoid system, which influences pain perception both directly and indirectly. CBD’s contact with glycine receptors as well as CB2 cannabinoid receptors, which are both implicated in the perception of pain, are two of the most well-known methods for this to happen.

While the cause of fibromyalgia is unknown, patients with the disorder have been found to have small fiber neuropathy, suggesting that neuropathy may play a role in fibromyalgia-related pain.

Glycine receptors are inhibitory receptors in the central nervous system that are involved in pain perception. CBD was discovered to potentiate these receptors in mouse research, reducing the perception of “chronic inflammatory and neuropathic pain.” These findings hold tremendous potential for the future, as nerve pain is one of the most difficult fibromyalgia symptoms to treat.

CB2 cannabinoid receptors are found predominantly outside of the central nervous system and are involved in immune response regulation, including inflammation. Mitigating an inflammatory response with CBD oil may ease some of the pain and sensitivity experienced by sufferers of disorders like fibromyalgia, which involves a complex combination of difficulties.

The potential of vaporized cannabis as an alternative to pharmaceutical treatment was studied in research on neuropathic pain conducted by the University of California. In terms of its analgesic qualities, cannabis scored comparably to two of the most often prescribed medicines in terms of pain reduction. CBD oil is a well-tolerated choice for fibromyalgia pain because it does not have the same side effects as many prescription drugs and does not have the intoxication effects of THC.

CBD Oil for Depression Caused by Fibromyalgia

Depression is a prevalent symptom of fibromyalgia, and while it does not impact all individuals who have been diagnosed, it is a common trait in any chronic condition. The effects of CBD oil on anandamide, adenosine, and serotonin levels have been found to increase mood and motivation.

The feel-good neurotransmitter anandamide, commonly known as the “bliss molecule,” is important for motivation and emotions of happiness. CBD oil reduces anandamide reuptake, allowing more of it to circulate through the brain and lessening the effects of depression.

CBD oil is also an adenosine reuptake inhibitor, a neurotransmitter that has calming, anti-inflammatory, and sleep-promoting properties. CBD oil may help to lower anxiety by allowing more of this neurotransmitter to remain in circulation, similar to how it affects anandamide.

Serotonin is the neurotransmitter that is arguably most closely related to depression. Depression has long been related to low levels of this mood-regulating neurotransmitter. Selected serotonin reuptake inhibitors are one of the most used medical therapies for depression (SSRIs). These drugs prevent serotonin from being reabsorbed, increasing the quantity of serotonin in the body. CBD oil has the potential to function in a similar way as SSRIs. CBD has been demonstrated to swiftly and effectively elevate serotonin levels in the brain by acting as an agonist on the serotonin receptor 5-HT1A, resulting in promising antidepressant effects.

Best CBD Oils for Fibromyalgia Treatment

You must know what to look for in order to discover the best CBD oil for fibromyalgia. Here are some pointers to assist you in selecting the most appropriate and high-quality CBD products:

Take a look at the THC content. CBD oil must be sourced from industrial hemp and have a THC concentration of 0.3 percent or below to be legal in the majority of US states. Only states that allow recreational use of cannabis can purchase products with greater THC levels. Your state’s cannabis and CBD laws can be found here.

Invest in organic products. If at all possible, choose a product that is made from organic hemp. Your goods will be clean and devoid of dangerous chemicals, pesticides, and herbicides as a result of this.

Look over the ingredients. Look for a product with the fewest possible ingredients. CBD oil typically consists of CBD, a carrier oil such as hemp seed oil or coconut (MCT) oil, plus terpenes or natural flavors. Take a pass if the CBD product you’re considering includes a lot of unnecessary ingredients or artificial additives.

Look for Certificates of Analysis (COAs): Companies should have their products tested in an independent laboratory and the results documented in a Certificate of Analysis. A COA will reveal the chemical composition of your CBD product, allowing you to confirm its purity, potency, and safety.

If you or someone you care about is suffering from fibromyalgia, it may be time to look into how CBD oil can assist.

The National Fibromyalgia Association (NFA) estimates that 10 million Americans suffer from fibromyalgia. Women are disproportionately affected; up to 90% of FM sufferers are women. Between the ages of 20 and 50, the condition is frequently discovered. Its prevalence, however, increases with age. So much so that the American College of Rheumatology estimates that up to 8% of Americans aged 80 and up have rheumatoid arthritis.

Patients are turning to CBD for fibromyalgia because it is a painful ailment. Antidepressants and pain medications, for example, focus on reducing symptoms and improving quality of life, but there is mounting evidence that CBD oil for fibromyalgia does the same.

One thing that no FM sufferer wants is to become addicted to painkillers. Misuse of these strong medications is rampant, with over 100 individuals dying each day from an opioid overdose in the United States. CBD for fibromyalgia could help you experience less pain with fewer negative effects and a lower chance of addiction. If you have fibromyalgia, this tutorial will look at the benefits of utilizing CBD.

What Is Fibromyalgia and How Does It Affect You?

“Is fibromyalgia an autoimmune disease?” you might wonder. ” is a frequently asked question. FM is not considered an autoimmune illness because it does not induce inflammation. Furthermore, no proof of fibromyalgia causing tissue damage has been discovered by studies. Because it has several symptoms with autoimmune disorders, it is sometimes misdiagnosed. FM can, in fact, arise in conjunction with an autoimmune condition.

Fibromyalgia is a condition that causes chronic pain in the body, according to a more exact definition. At the time of writing, the exact cause was unknown. Many specialists believe, however, that it leads the brain to perceive pain at a higher degree. FM symptoms may appear only after a period of considerable psychological stress, physical trauma, or surgery in some patients. Symptoms arise and increase over time in some people with no identified cause.

Anxiety, irritable bowel syndrome, and tension headaches affect a large percentage of people with FM.

When you are injured, nerve signals flow from the affected area to the brain via the spinal cord. Your brain interprets these signals as pain and alerts you to the fact that something is wrong. When you heal, you have reduced discomfort, which eventually fades entirely. However, if you have fibromyalgia, you will have pain even if you are not injured or sick. Doctors are baffled as to why it persists.

One probable explanation is that the brain’s processing of pain signals has a flaw. FM patients may have more pain-sensing cells than the general population. They may also have fewer pain-suppressing cells. As a result, pain signals are constantly active, and tiny bumps produce far more discomfort than they should.

Fibromyalgia Symptoms

The list of probable fibromyalgia symptoms is long, but the most prevalent is generalized discomfort. It’s commonly described as a dull discomfort that lasts at least three months, according to patients. If the pain occurs on both sides of the body, below and above the waist, it is considered “widespread.”

One of the most common symptoms of fibromyalgia is fatigue. Even if they sleep for significant periods of time, FM patients often feel exhausted when they wake up. Patients’ sleep is disrupted by pain, which is one of the causes of this problem. In FM patients, sleep disturbances such as restless leg syndrome occur on a regular basis.

Cognitive issues, such as an inability to pay attention or focus, may also be present. Fibro fog is a term used to describe this ailment. Other painful symptoms that can coexist with FM include:

  • Disorders of the temporomandibular joint (TMJ)
  • Irritable bowel syndrome (IBS) is a type of irritable bowel syndrome
  • Migraines are a type of headache
  • Bladder pain syndrome

Fibromyalgia: What Causes It?

Physicians, unfortunately, have limited knowledge of the exact cause(s) of fibromyalgia. Problems in the body’s pain signals could be caused by a number of factors. It’s also possible that FM is caused by a combination of factors. Here are several examples:

Factors of heredity:

It’s been suggested that FM runs in families. Your parents, for example, could pass on genes that make you more sensitive to pain. Some genes are linked to an increased risk of depression or anxiety.

Other diseases:

Sickness such as an infection or arthritis increases your chances of developing FM.

Emotional or physical abuse:

If you were abused as a youngster, you’re more likely to acquire fibromyalgia later in life. One reason is that abuse alters the brain’s response to stress and pain.


Many people suffer from posttraumatic stress disorder (PTSD) as a result of a stressful experience, such as a car accident. In certain patients, there is a relationship between a stressful incident and FM.


Women are seven to nine times more likely than men to get FM. This statistic could have societal implications. Suffering affects men and women differently, and society has distinct expectations for how each gender handles pain.

Anxiety and Depression:

Anxiety and depression have been linked to FM. However, there is no strong evidence that they are the cause of the disease.

Lack of Exercise:

Not getting enough exercise is a possible cause of FM! People who do not exercise are considerably more likely to get the illness than those who are physically active.

Treatments for Fibromyalgia Pain

FM is usually treated with a combination of self-care and medication. The goal is to promote overall health while reducing symptom severity. There is no single treatment that can help with all of the symptoms. The main reasons for using medications for FM are to promote sleep and reduce discomfort. Among the possibilities are:


Savella and Cymbalta are two antidepressants that can aid with weariness and pain. A muscle relaxant can help you sleep, and a traditional antidepressant can help you feel better.

Pain relievers:

Opioids are used by some patients, but it is all too simple to get addicted to them. Advil and Aleve, as well as other over-the-counter pain relievers, are more widely used.

Anti-Seizure Drugs:

Drugs used to treat epilepsy (anticonvulsants) are increasingly being recommended to fibromyalgia patients. Pregabalin was approved by the FDA to treat FM, and gabapentin is also widely used.

Physical Therapy:

Physical therapy has proven to be beneficial for some people. Exercises to develop stamina, strength, and flexibility are taught by a therapist. There is occupational therapy, which entails adopting lifestyle modifications to alleviate physical stress. You can also talk to a counselor to get some advice on how to deal with the circumstance.

There is a trend toward using complementary and alternative medicine to treat FM. Acupuncture appears to aid with symptoms in certain cases. Massage treatment, yoga, and tai chi are some more alternatives. In general, you should make an effort to:

  • Reduce your stress level
  • Make an effort to obtain enough rest
  • Exercise on a regular basis
  • Maintain a healthy diet and lifestyle

CBD oil for fibromyalgia is an innovative technique to deal with symptoms. Proponents suggest that the cannabinoid can help people sleep better and lessen pain.

Fibromyalgia and CBD Oil

Despite the fact that millions of people suffer from FM, nothing is known about it or how to best treat it. The list of symptoms is long, and it’s usually broken down into the three categories mentioned before. Here’s a quick rundown:

  • Widespread suffering
  • Fatigue

Problems with cognition

Is there proof that CBD can help with all three features of fibromyalgia? CBD and fibromyalgia, according to recent studies, do mix. Serotonin receptors are thought to be activated by cannabidiol. CBD may aid in the reduction of inflammation, the regulation of body temperature, and the feeling of pain. It may also help with anxiety and depression symptoms, as well as sleep.

It’s simple to see the appeal when there are so many possible benefits. What type of CBD is best for fibromyalgia depends on what you’re searching for. CBD oil is inexpensive and simple to use. Edibles take longer to work, but the effects might endure for hours. According to some users, vaporization has a reasonably high bioavailability and has an effect in seconds.

The optimum CBD dosage for fibromyalgia is different for everyone. Taking anywhere from 10mg to 200mg per day could make you ‘feel’ something. Begin with a modest dose and gradually increase it. As soon as you notice something, you should stop increasing. Let’s look at how CBD oil can help with each of the three types of fibromyalgia symptoms.

Fibromyalgia and CBD: Pain Relief

There are a limited number of studies on fibromyalgia and CBD in general. The legalization of hemp could spur more study into CBD oil as a treatment for fibromyalgia pain. In August 2017, Njis J. published a study on CBD for pain in Expert Opinion on Therapeutic Targets. It was concluded that CBD could help individuals with chronic pain by reducing the responsiveness of cells surrounding neurons. Patients with FM were included in this discovery.

Gruber S. is now conducting a clinical trial. It started in September 2019 and involved 55 chronic pain sufferers. The investigation is expected to be completed by August 2021. Hopefully, it will provide us a better understanding of how CBD can aid patients suffering from fibromyalgia.

Sleep and Fatigue with CBD for Fibromyalgia

For many FM sufferers, sleep deprivation is a severe problem. It causes extreme weariness, irritation, and a slew of other health problems. CBD appears to be linked to a reduction in weariness.

In 2019, Shannon et al. published one of the most important CBD for sleep research in The Permanente Journal. 103 adult patients with anxiety and poor sleep habits were given CBD by the researchers. The study was completed by 72 volunteers. A decrease in anxiety was noted by 79 percent of them. Within a month, two-thirds of patients reported improved sleep scores, albeit this number fluctuated over time.

In July 2016, Walitt B. released a new study on CBD oil for fibromyalgia in The Cochrane Database of Systematic Reviews. The study’s purpose was to look at cannabis’ safety, effectiveness, and tolerability in FM patients. It focused on the effects of Nabilone, a cannabis derivative created by humans.

There was no clear unbiased evidence that Nabilone was effective in the treatment of FM, according to the researchers. The findings of studies focusing on CBD from hemp need to be seen. If such a study reveals advantages, can we conclude that lab-grown cannabis is inferior to the actual thing?

Inflammation, Pain, and Fibro Fog: CBD for Fibromyalgia

A small number of CBD fibromyalgia studies investigate if the cannabinoid can aid with inflammation and fibro fog. The term “brain fog” refers to a variety of cognitive disorders. It occurs when the limbic system of the brain fails. Phospholipid damage is also caused by brain injury. These phospholipids form membrane barriers that keep charged particles at bay. Our brain malfunctions as a result of their deterioration.

This condition might be caused by hormonal changes caused by andropause or menopause. Sex hormones aid in the regulation of cortisol, a stress hormone that alters neurotransmitters in the brain. As a result, blood circulation and metabolism are slowed. CBD may assist to lower brain inflammation, which is thought to be a major cause of fibro fog in FM patients.

CBD oil has been studied in the treatment of fibromyalgia pain. The safety and efficacy of cannabis in FM were investigated in a study published in the Journal of Clinical Medicine by Sagy I. It came to the conclusion that medical cannabis could be both safe and beneficial for those suffering from fibromyalgia.

The majority of CBD for inflammation research has been done on rats and mice. Genaro K. investigated the effects of CBD on pain in rats in a study published in Frontiers in Pharmacology in 2017. Oral CBD medication dramatically reduced sciatic nerve pain and inflammation, according to the study.

CBD and Fibromyalgia: Some Final Thoughts

FM is a serious disorder that causes extreme pain and suffering, despite the fact that it is not an autoimmune disease. Because there is no treatment for the sickness, people are desperate to find anything that may help them manage their symptoms. Painkillers, antidepressants, and therapy are all common therapies. Acupuncture and massage treatment are two other choices.

There is a current trend of using CBD oil to treat fibromyalgia. Cannabinoid supporters claim that it relieves problems like chronic pain, sadness, anxiety, and fibro fog. It’s also been suggested that it can help with sleep deprivation. If you’re interested in taking CBD for fibromyalgia, talk to your doctor first and start with a low dose.