CBD Oil for Inflammation

October 22, 2021

CBD is a non-psychoactive and highly therapeutic cannabinoid present in the cannabis plant that is used to treat a variety of ailments.

Every year, thousands of papers describing the use of CBD for various health issues are published. Every year, it appears like we’re adding more medical diseases to the list of CBD’s applications.

How can a single substance be effective for so many distinct medical conditions?

CBD treats a variety of disorders through a variety of techniques. Its anti-inflammatory properties are by far the most striking benefit it provides.

CBD’s anti-inflammatory properties are incredibly strong, affecting dozens of different inflammatory processes at the same time.

CBD Oil For Inflammation Is The Best

1. CBD Oil Royale

Between 250 and 1000 mg

8.3 mg/mL to 33.3 mg/mL

a range of $0.15 to $0.26

2. CBD Capsules from Charlotte’s Web

210 – 6000 milligrams

a concentration of 7–60 mg/mL


3.CBD Drops for Social Use

1000 milligrams

33.33 milligrammes per millilitre


4.Hello and good morning

900 milligram

30 micrograms per milliliter


5.Turmeric Curcumin Oil + CBD Oil Nano Tincture by Phoria

a dose of 300 to 5000 mg

ten to eighty-three milligrams per milliliter


6.Nordic Oil Curcumin & Piperine Full-Spectrum CBD Oil

1500 milligram

150 micrograms per milliliter


Is CBD Effective in Reducing Inflammation?

Inflammation in the body is caused by a complex network of chemical messengers and enzymes.

Blocking one pathway may be beneficial for some types of inflammation, but it is not the most efficient treatment technique.

CBD is a great anti-inflammatory since it works on numerous levels. CBD does this by halting the inflammatory process at many points throughout the process.

CBD is more effective in combating inflammation than typical anti-inflammatory pharmaceuticals like aspirin, which inhibits only one enzyme involved in the inflammatory process.

101 on Inflammation

Trillions of individual cells make up the human body, and they all function together. As a result, the cells must be able to communicate with one another.

We use our nervous system to deliver messages to and from our brain in the form of electrical impulses, and we employ chemical messengers to send signals throughout the body via the bloodstream.

The immune system and blood flow to injured parts of the body are significantly reliant on these chemical messengers to signal inflammation.

There are dozens of inflammatory messengers, each of which sends a different message — some summon immune cells to a site to assist clean up an infection, while others instruct the circulatory system to begin pooling blood in a damaged location.

Allergic reactions, for example, rely on the activation of mast cells, which patiently wait for an allergen to float nearby before becoming activated. When a cell is exposed to an allergen, it produces a large number of inflammatory markers (such as histamine), which trigger a chain of inflammatory reactions known as an allergic reaction (for example, hives, runny nose, puffy eyes, or scratchy throat).

The inflammatory process is depicted in this diagram. Isn’t it complicated?

(Cavaillon and colleagues, 2002)

“I have no idea what any of this means,” you may be thinking.

You’re not alone, to be sure.

Researchers are continuously learning more about inflammation, and there are still some types of inflammation that we don’t fully comprehend (such as interstitial cystitis and irritable bowel syndrome, for example).

The type of inflammation is taken into account while determining the optimal treatment for inflammation.

We must determine whether the inflammation is acute (short-term) or chronic (long-term) (long-lived). We must also consider if the inflammation is the result of physical injury or an allergy or autoimmune reaction. Because each of these types of inflammation includes different chemical messengers, these are important things to consider.

To stop inflammation, these chemical messengers must be blocked.

Inflammation can be divided into two types.

Depending on the origin of inflammation – autoimmune, allergic reactions, traumatic injuries, and infection — it can take many various forms.

The most crucial distinction to make is between acute (short-term) and chronic inflammation (long-term).

1. Inflammation that is sudden and severe

Acute inflammation is inflammation that lasts for a short period of time, usually less than six months. We experience acute inflammation when we develop cuts on our skin or stub our toe. It appears quickly and then fades away once the wounded has healed.

  • If the irritant persists, acute inflammation might progress to chronic inflammation (such as eating inflammatory foods on a regular basis).
  • The following are some of the most common causes of acute inflammation:
  • Reactions due to allergies
  • Asthma flare-ups
  • Injuries caused by trauma
  • Eczema is a skin condition that affects millions of people (can also become chronic)
  • Arthritis in its early phases
  • Depression in its early phases

Histamine, nitric oxide, and inflammatory enzymes like COX and 5-LOX are the most important messengers in acute inflammation. For example, aspirin works by inhibiting the COX enzyme.

CBD inhibits the COX enzymes (both COX-1 and COX-2) that make inflammatory messengers such leukotrienes and prostaglandins, which are important mediators in both acute and chronic inflammation.

2. Inflammation that lasts a long time

  • Chronic inflammation is defined as symptoms that last longer than six months.
  • Inflammation that lasts for a long time can harm the systems involved.
  • Chronic inflammation operates like this in a nutshell:
  • Inflammation causes tissue damage.
  • To repair the damage, the tissue releases new inflammatory messengers.
  • The tissue is further damaged by the new inflammation.
  • The procedure is repeated
  • With a variety of medical diseases, chronic inflammation can last for years, including:
  • Depression
  • Parkinson’s disease is a neurological disorder that affects people.
  • Multiple sclerosis (MS) is a disease that affects people
  • Osteoarthritis
  • Rheumatoid arthritis is a type of arthritis that affects the joints.
  • Inflammatory bowel disease (IBD) is a type of bowel disease that
  • Psoriasis
  • Hepatitis
  • TNF-a, NF-kB, IL-6, and IFN-y are some of the key inflammatory messengers implicated in chronic inflammation. All of these inflammatory signals have been demonstrated to be inhibited by CBD.

Inflammation Treatment Options

Because inflammation is so widespread, we’ve developed a number of various techniques to treating it over time.

Inflammation can be treated in a variety of ways, including:

1. Dietary Modifications

Remove foods that cause inflammation from your diet.

Identify and remove food allergy triggers.

Increase the amount of fiber and antioxidant-rich foods in your diet.

Increase your intake of anti-inflammatory foods (such as turmeric or ginger)

2. Anti-inflammatory Drugs (ADRs)


NSAIDs (nonsteroidal anti-inflammatory drugs) (Aspirin, Ibuprofen, and Acetaminophen)

Inhibitors of TNF (Adalimumab, and Etanercept)

3. Supplements with herbs

Extracts of cannabis (CBD, CBN, and THC)

the root of ginger (Zingiber Officinalis)

Resin of Frankincense (Boswellia serrata)

The root of the turmeric plant (Curcuma longa)

Aloe vera (Aloe vera)

4. Changing Your Way of Life

Gentle aerobic exercise is recommended

Techniques for reducing stress


Sleep hygiene is really important

CBD for Inflammation: A Step-by-Step Guide

CBD is an anti-inflammatory that works at practically every level of the inflammatory response, interfering with inflammatory signals.

CBD can penetrate and stop inflammation on multiple levels for a variety of reasons:

  • It prevents the breakdown of anandamide, a potent anti-inflammatory peptide found throughout the body.
  • Many of our inflammatory signals are structurally similar to CBD (and other cannabinoids) (similar to our prostaglandins and leukotrienes).
  • CBD activates vanilloid receptors, which control a variety of inflammatory messengers (TNF-a, IL-4, and IL-12).
  • It inhibits the activation of immune cells like T and B cells [1], which are responsible for autoimmune inflammation.
  • CBD causes immune cells engaged in chronic inflammation to undergo apoptosis (programmed cell death).

CBD Interacts With Which Inflammatory Messages?

Unlike conventional anti-inflammatory drugs, which target only a some of the inflammatory messengers which really cause inflammation, CBD targets nearly all of them.

That makes it effective for a wide range of inflammatory conditions, including allergic reactions and autoimmunity, as well as strains and sprains.

CBD Has an Impact on Inflammatory Messages

Cannabinoids Inhibit Inflammation by Acting as Inflammatory Messengers

THC contains histamine, which is related to allergic reactions as well as causes fast inflammation.

IFN- is a protein that plays a big role in keeping chronic inflammation going.

NF-kB is a major sustaining element for psoriasis that also plays a role in cancer progression.

IL-4 is implicated in autoimmunity and regulates the transformation of T-helper cells to Th2 cells.

In acute inflammation, IL-6 initiates an inflammatory cascade, and it is a sustaining element in severe inflammation and autoimmune.

CBD Involved in acute inflammation caused by infectious diseases (bacteria or virus) IL-8 Involved in acute inflammation caused by infectious diseases (viruses or bacteria)

IL-12 is involved in autoimmune diseases such as rheumatoid arthritis.

THC THC is both an inflammatory and anti-inflammatory messenger, depending on the other messengers involved.

Prostaglandins are one of the most important regulators in the inflammatory response’s induction and progression.

Leukotrienes are one of the essential regulators in the inflammatory response’s onset and maintenance.

As you can see, CBD as well as many other cannabinoids have quite a lot to offer when it comes to inflammation, and they can help with a diverse selection of inflammation.

Because other cannabinoids have unique anti-inflammatory benefits, it’s recommended to look for a full-spectrum extract rather than a pure CBD extract when treating inflammatory diseases.

The Most Effective Inflammation CBD

CBD exists in a range of formulations, though not all of them are suitable for all conditions. There are a few varieties of CBD that really perform better than most when it pertains to inflammation.

Let’s go over the many varieties of CBD you’re likely to come across, as well as its benefits and drawbacks in terms of lowering inflammation.

1. Tinctures & CBD Oils

CBD oils seem to be the most popular CBD product on the market today. These have quite a long lifespan and enable simple, effective dosage. The tinctures seem to be closely related to oils, except instead of oils, they employ alcohol as the carrier. This provides them a longer shelf life and allows naturopaths and herbalists to include other anti-inflammatory botanicals into the formula more easily; nevertheless, the flavor is disagreeable.

To use CBD tinctures and oils, use the provided dropper to measure out the desired dose and apply underneath the tongue for a quick effect, or gulp down for a delayed effect.

2. CBD Capsules

CBD pills are another common CBD delivery route. They remove a lot of guessing from dosing and keep it simple to take CBD with you on the go.

3. Suppositories with CBD

CBD suppositories aren’t widely used, but they’re an effective way to treat intestinal inflammation by providing cannabinoids straight to the source of the problem.

4. Topical Products

CBD can be taken internally to treat unwanted skin inflammation. The recommended remedy for these issues, meanwhile, is generally topical. This permits the cannabinoid to direct their effects on the inflammatory tissues in the immediate area.

When Should You Use Topical CBD?

  • Psoriasis
  • Eczema
  • Allergic dermatitis
  • Acne
  • Muscle strains
  • Tendonitis
  • Infections of the skin

5. CBD Edibles are a type of CBD product

Edibles, like candy, biscuits, and cooking oils, are also effective ways to deliver CBD into the body. They have a nice flavor without sacrificing power. The big downside is that, excluding standardized gummies, determining the potency of edibles can be difficult. Because of the high glycemic index, consuming very many edibles could have other detrimental long-term health effects.

As a result, edibles seem preferable for spot treatment than as a daily CBD dose.

6. Vape Oils with CBD E-Liquids

Because absorption via the lungs is substantially higher than via the digestive tract, vape CBD is by far the most effective of all the dose forms.

However, getting started with vaping can be expensive but you’ll need to acquire a vaporizer, as well as the effects last less time than CBD taken orally.

Vaping is a good way to get CBD into your lungs and is thus a viable alternative for lung inflammation. However, CBD vape oil does or doesn’t worsen illnesses such as asthma, so proceed with caution when using them.

I’m not sure of the amount of CBD to Consume

More the CBD, the better whenever it pertains to inflammation. The majority of studies on cannabinoids and inflammation suggest a daily dosage response. It, therefore, means that the greater the anti-inflammatory impact, the more you take.

As a result, the suggested dose will differ depending on the severity of the inflammation.

Low strength may provide the desired benefits for low-grade inflammation, such as the early stages of arthritis.

You may need to use a high or medium potency to alleviate severe inflammation, including autoimmune illnesses or inflammatory bowel disease.

CBD with a low concentration of THC, CBD with a medium concentration of THC, and CBD with a high concentration of THC

Arthritis in its early stages
  • Illness after a viral infection
  • Mild allergies • Low-grade traumatic injuries
Rheumatoid Arthritis
  • Multiple sclerosis (MS) • Mild depression
  • Atherosclerosis (heart disease)
  • Hepatitis is a disease of the liver.
  • Allergic reactions that are severe
  • Depression that is moderate
  • Parkinson’s disease (PD)

Using Weight to Calculate CBD Dosage Strengths

Low Strength Medium Strength High Strength Unit of Measure

Imperial (pounds) 1 milligram per ten pounds 3 milligrams per ten pounds 6 milligrams per ten pounds

Metric (kilogrammes): 1 mg per 4.5 kg, 3 mg per 4.5 kg, and 6 mg per 4.5 kg

You can estimate the dose you’ll need based on these broad guidelines to receive the level of anti-inflammatory support you’re searching for.

It’s crucial to remember that these are only suggestions, and your dose may differ.

As a result, these guidelines are intended to provide you an approximate idea of how much you’ll need.

After you’ve determined the strength you’ll need, use your weight to determine how much CBD you’ll need per day (in mg).

Remember, these are pure CBD dosages; use these numbers to figure out how many edibles, CBD oil, or capsules, you’ll need to receive the proper quantity of CBD.

CBD’s Potential Negative Effects

Despite the fact that CBD has been shown to be extremely safe in terms of toxicity, it’s crucial to be aware of the potential adverse effects. Everyone is unique, and what works for one person may not necessarily work for another.

Here are a few of the most typical CBD side effects:

  • Suppression of appetite
  • Diarrhea
  • Drowsiness
  • Mouth is parched
  • Lightheadedness
  • Reduced heart rate
  • Sedation

Conclusion: CBD Can Help With Inflammation

CBD is an effective anti-inflammatory substance, and it is used to treat a variety of inflammatory conditions.

CBD is effective against the following types of inflammation:
  • Autoimmunity
  • Reactions due to allergies
  • Soft tissue damage caused by trauma
  • Strains in the muscles
  • Inflammatory bowel disease (IBD) is a type of bowel disease that
  • Atherosclerosis
  • Inflammation following surgery

The key to using CBD efficiently for inflammation is to make sure you’re only using high-quality, full-spectrum extracts that have undergone third-party testing to verify they’re devoid of impurities.

To receive anti-inflammatory benefits, you can use almost any kind of CBD, but we recommend looking for a high-potency oil because of its ease of use, cost-effectiveness, and long shelf-life.

Inflammation is a part of the body’s defensive mechanism, and it involves the immune system identifying and eliminating dangerous chemicals. Short-term (acute) and long-term (chronic) inflammation exist. According to the World Health Organization, chronic inflammatory disorders are the leading cause of death worldwide (WHO).

An estimated 125 million Americans were dealing with a chronic illness at the turn of the century. Sixty-one million people had multiples! In 2014, it was projected that 60 percent of Americans have a chronic illness. Chronic inflammatory illness is responsible for 60% of fatalities worldwide. Cancer, heart disease, diabetes, and obesity are just a few examples.

Because of the widespread nature of the illness, manufacturers of nonsteroidal anti-inflammatory drugs (NSAIDs) profit handsomely. However, not all of these medications are effective. They can also cause a slew of unpleasant side effects, including elevated blood pressure and headaches. This could be one of the reasons why CBD oil for inflammation has become so popular.

CBD’s anti-inflammatory effects have made it a feasible alternative for a wide range of patients. It is non-intoxicating, with very minor adverse effects observed thus far. Inflammation is linked to a wide range of disorders and symptoms, and preliminary research suggests that CBD can help with inflammation. Continue reading to find out more.

What Is Inflammation and How Does It Affect You?

The white blood cells of the body, as well as the compounds they generate, are involved in the inflammatory process. Viruses, bacteria, and other alien species are all protected by these cells. Even when there is nothing to attack in certain inflammatory disorders, such as arthritis, our immune system triggers an inflammatory response.

Our immune system damages itself as a result of these autoimmune disorders. When the body believes healthy tissues are sick, it reacts as if it were confronted with a true threat. Inflammation isn’t necessarily a harmful thing in the body. In the event of autoimmune illnesses, however, it becomes a major issue. Hepatitis, inflammatory bowel disease, and celiac disease are examples of inflammatory illnesses.

What Are the Causes of Inflammation?

During the inflammation process, chemicals from the body’s white blood cells are released into the blood or damaged tissues. In general, this procedure aids in the protection of your body against pathogens. When these substances are released, blood flow to the illness or injury site is boosted. At this stage, you may detect a reddish tint or a heated sensation. Some of the substances can cause a fluid leak into the tissues on occasion. Swelling occurs as a result.

The increased number of cells and inflammation cause joint irritation over time. Swelling of the joint lining and cartilage wear are among the complications that follow.

Inflammation can be divided into two types: acute and chronic.

Acute Inflammation: Harmful substances, microbial invasion, or trauma cause damage to your tissue. The symptoms appear swiftly and become severe in a short period of time. Inflammation that is ‘subacute’ is also present. This is the time between acute and chronic inflammation, and it usually lasts 2-6 weeks.

Chronic inflammation is a type of long-term inflammation that can persist anywhere from a few months to several years. Chronic inflammation has different consequences and causes different difficulties depending on the type of injury. The ability of your body to heal itself is equally important.

Human inflammation has been studied for thousands of years. Intriguingly, a Roman physician called Aulos Cornelius Celsus documented the four indications of inflammation in the first century AD:

  • The dilatation of tiny blood vessels at the site of damage causes redness.
  • Increased blood flow solely in the skin and other peripheral areas of the body causes heat.
  • Swelling refers to the buildup of fluid outside of the blood vessels.
  • Pain is induced by the swelling of the tissues, which causes them to deform. Prostaglandins and serotonin, for example, are chemical mediators of inflammation.

Inflammation Symptoms

Inflammation can cause a variety of symptoms, including:

  • Pain
  • Redness
  • Immobility
  • Inflammation of the joints
  • Heat

You might also have flu-like symptoms like:

  • Chills
  • Fever
  • Fatigue
  • Muscle tenseness
  • Headaches
  • Appetite loss.

Inflammation might affect your organs if you have an autoimmune illness. Symptoms vary depending on which organ is affected:

  • Inflammation of the kidneys can lead to renal failure or excessive blood pressure.
  • Shortness of breath could be caused by lung inflammation.
  • Fluid retention may occur as a result of heart inflammation (myocarditis).

Chronic inflammation is linked to a number of risk factors. These are some of them:

Increased amounts of inflammatory chemicals have been linked to the aging process.


If you eat a diet strong in trans-fats and saturated fat, your body will manufacture more of these molecules. Obesity raises your chances of developing inflammation. Endocrine organs include fat tissue. Multiple adipokines, as well as inflammatory mediators, are secreted.


Smokers create fewer anti-inflammatory chemicals than non-smokers.

Sleep disturbances and stress:

Emotional and physical stress have been linked to the production of inflammatory cytokines. Sleep disturbances can also be caused by stress. People who have irregular sleep schedules have a higher risk of chronic inflammation than those who sleep on a regular basis.

Low Sex Hormones:

Estrogen, testosterone, and other sex hormones have been shown to reduce the production and secretion of inflammatory markers.

Therapy for Inflammation

For disorders like arthritis, where inflammation is a factor, there are a variety of therapeutic choices. Treatment usually has the following objectives:

  • The underlying illness process can be slowed or corrected.
  • Any activity that aggravates pain should be modified or avoided.
  • Pain-relieving medications are used.
  • Physical therapy can help you keep your muscle strength and joint mobility.
  • Reduce joint tension by wearing splints, canes, or braces.

Anti-inflammatory medications relieve pain by reducing swelling and inflammation. The effects of the various medications are frequently inconsistent. As a result, a doctor may prescribe drugs from several different classes. Among the many examples:

  • Prednisone is a common choice of corticosteroids.
  • Abatacept, infliximab, and Rituximab are examples of biologics.
  • Medications that treat rheumatoid arthritis, such as azathioprine and sulfasalazine, are known as disease-modifying antirheumatic drugs (DMARDs).
  • Ibuprofen, aspirin, and Naproxen are examples of nonsteroidal anti-inflammatory drugs or NSAIDs.
  • Hydrochloroquine is a common antimalarial medication.

Inflammation and diet have a strong correlation. Controlling your diet and drinking habits is critical for treating and controlling any inflammatory illness. If you’re overweight, a smart and healthy lifestyle involving a healthier lifestyle and more exercise can make a significant difference. Think about this:

Limit fructose corn syrup and refined carbohydrates in your diet for a low-glycemic diet.

Nuts: Snacks like almonds can help you avoid diabetes and heart disease. Consume more brussels sprouts, apples. blueberries and cabbage as vegetables and fruits.

Fiber: The high fiber diet decreases particular chronic inflammation.

Inflammatory indicators are also reduced by consuming more Omega-3 fatty acids, such as fish oil.

Exercise reduces a range of pro-inflammatory chemicals in humans, regardless of weight loss, according to human clinical investigations. CBD oil for inflammation, according to recent studies, could also be beneficial.

Inflammation and CBD Oil

CBD for inflammation has been shown in studies to help people experience less chronic pain. It accomplishes this by interfering with the activation of our endocannabinoid receptors. Cannabidiol reacts with the neurotransmitters in the body, resulting in a reduction in inflammation. Several human investigations have linked the use of THC and CBD together with significant pain alleviation.

The effect of transdermal CBD on rats was investigated in a study published in the European Journal of Pain in July 2016. Researchers used CBD gels of various strengths to treat the afflicted areas of animals with arthritis. For four days in a row, the intensities were 0.6, 3.1, 6.2, and 62.3 mg.

Transdermal CBD gel reduced significantly swelling in the joints, posture of limb scores mostly as evaluation of spontaneous pain, and much more, according to the findings. Topical CBD provides “therapeutic promise for the treatment of arthritis pain-related behaviors and inflammation,” according to the study. Furthermore, no evidence of negative side effects was found with CBD.

Bruni N. examined several cannabis systems of delivery for pain plus inflammation management in research reported in Molecules in October 2018. It was a study review that looked at new breakthroughs in the use of cannabis delivery techniques to treat inflammation.

The researchers stated that their peers published over 1,000 studies every year on the subject. Based on current evidence, combining THC and CBD may result in “rapid systemic effects and long-term outcomes.” Intranasal cannabis sprays were also found to be very effective in the treatment of inflammation.

Is Cannabidiol (CBD) Used to Treat Inflammation?

Yes, to put it succinctly. CBD has anti-inflammatory properties, according to an increasing number of researchers. CBD is a non-psychoactive chemical found in marijuana and hemp. It doesn’t give you the same euphoria as THC does. CBD oil for inflammation may possibly be as beneficial as over-the-counter anti-inflammatories, according to some research.

Combining CBD with curcumin is becoming increasingly popular. There’s also evidence that it’s anti-inflammatory and antioxidant. Combining two chemicals with these advantages should, in theory, be extremely beneficial. Bioavailability is low for both in practice.

You can improve it by changing the way you consume your food. Vaporized CBD, for example, absorbs more quickly than CBD taken orally or sublingually. A cutting-edge nano-emulsification procedure is also in use. It entails reducing and suspending small droplets of CBD oil in order for them to easily pass through cell membranes.

‘How much CBD oil should I take for inflammation?’ is a question that many people have. It’s difficult to answer this question. The reason for this is that the amount you require is determined by a variety of variables. Weight, general health, and metabolism are just a few examples. To begin, start with a small dosage of CBD, perhaps 2.5-5mg per day. As needed, up the amount. In the end, you may require anything between 10 and 100 mg each day!

Last Words

Inflammation and oxidative stress are key factors in the development of many human diseases. It’s difficult to come up with a solution because both problems feed off one other. The plethora of medications available to us isn’t helping issues. Inflammatory disorders would not spread as quickly if these drugs were genuinely beneficial. The growing popularity of CBD oil as an anti-inflammatory treatment reflects people’s dissatisfaction with standard medications.

CBD for inflammation appears to be useful, according to a growing body of studies. Don’t mistake cannabidiol for a magic potion,’ though. Taking it while continuing to live an unhealthy lifestyle is a recipe for failure. In addition to a good diet and frequent exercise, we recommend utilizing CBD for inflammation.

Unfortunately, further research is needed to prove CBD’s potential anti-inflammatory effects. Until that time comes, the FDA will only approve Epidiolex, a Big Pharma product. We hope that common reason prevails and CBD becomes federally legal as soon as possible.